GI Balance

ADULT

ENTERAL

NUTRITION

Products

Novasource^Ⓡ GI Balance

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A sole source of nutrition with PHGG to further support blood glucose management and a healthy gut microbiota

Recent position statements and guidelines support the use of diabetes specific formulations for patients requiring support in the management of blood glucose.

Re-formulated to improve tolerance whilst addressing specific needs of patients facing abnormalities in blood glucose such as diabetes and stress hyperglycemia.

The key elements of Novasource^®

Gi Balance/Balance Plus compared to standard tube feeding are:

Lower carbohydrate content; Total Energy (TE) 32-39% including slowly digestible carbohydrate, isomaltulose, to help manage blood glucose response⁴⁶
Inclusion of 100% soluble PHGG fiber 20-22g/L
High quality protein TE 18-20%
Higher Fat content, TE 39-45%, enriched in unsaturated fatty acids, especially monunsaturated fatty acids (MUFA)

Reduction in available carbohydrate content with simultaneous increase in the MUFA content has demonstrated positive outcome on lipid management and glucose control.

Novasource Gi Balance and Novasource Gi Balance Plus may be used as sole source nutrition.

Key Fact Block

Isomaltulose enriched
carbohydrate blend

Slowly hydrolysed by intestinal enzymes allowing for slow release of glucose
Low glycemic response to help control blood glucose
Naturally occurring in honey and sugar cane juice⁴⁷

Adapted Lipid Blend

High amount of mono unsaturated fatty acids (MUFA)

known to improve glycaemic control and lipoprotein profiles in type II diabetes patients⁴⁸

Low Saturated Fatty Acids (SFA) and Trans fat

a diet with decreased SFA and increased MUFA, was shown to improve insulin sensitivity⁴⁹

Meets EPA/DHA* requirements^50-52

High Quality Protein

100% milk protein
Protein Digestibility Corrected Amino Acid Score (PDCAAS)** = 1.0

meaning it contains all essential amino acids in quantities that correspond to human requirements at higher concentrations than in the reference scoring protein

Partially Hydrolysed
Guar Gum (PHGG)

To prevent enteral nutrition induced diarrhoea in post surgical and in critically ill-patients supplementing enteral nutrition with PHGG is effective (Level A Recommendation)⁵³
PHGG can be used successfully in patients in enteral nutrition lowering the incidence of diarrhoea. PHGG has been proven to be safe and effective in promoting gut health<⁵⁴
Has been shown to have an effect on plasma blood glucose

References

Velázquez M., et al., Effect of Oligosaccharides and Fibre Substitutes on Short-chain Fatty Acid Production by Human Faecal Microflora. Anaerobe 2000 vol: 6 (2) pp: 87-92;
Alam N., et al., Partially hydrolyzed guar gum-supplemented oral rehydration solution in the treatment of acute diarrhoea in children. Journal of pediatric gastroenterology and nutrition 2000 vol: 31 (5) pp: 503-507;
Topping D. & Clifton P., Short-Chain Fatty Acids and Human Colonic Function: Roles of Resistant Starch and Nonstarch Polysaccharides. Physiological Reviews 2001 vol: 81 (3) pp: 1031-1064;
Yoon S., et al., Physiological Functions of Partially Hydrolyzed Guar Gum. J. Clin. Biochem. Nutr. 2006 vol: 39 pp: 134-144;
Mesejo, A., et al., Comparison of a high-protein disease-specific enteral formula with a high-protein enteral formula in hyperglycemic critically ill patients. Clinical Nutrition, 2003. 22(3): p. 295-305;
Takahashi H., et al., Effect of partially hydrolyzed guar gum on fecal output in human volunteers. Nutrition Research 1993 vol: 13 (6) pp: 649-657;
Wells C. et al., Effect of fiber supplementation of liquid diet on cecal bacteria and bacterial translocation in mice. Nutrition 1992 vol: 8 (4) pp: 266-71;
Takahashi H., et al., Influence of partially hydrolyzed guar gum on constipation in women. Journal of nutritional science and vitaminology 1994 vol: 40 (3) pp: 251-9;
Lochs H, et al. Introductory to the ESPEN Guidelines on Enteral Nutrition: Terminology, definitions and general topics. Clin Nutr 2006;25(2):180-186;
Meier R, Gassull M. Consensus recommendations on the effects and benefits of fibre in clinical practice. Clin Nutr Suppl 2004;1(2):73-80;
Meier R, Gassull M. Consensus recommendations on the effects and benefits of fibre in clinical practice. Clin Nutr Suppl 2004;1(2):73-80.
Lampe JW, et al. Gastrointestinal effects of modified guar gum and soy polysaccharide as part of an enteral formula diet. J Parenter Enteral Nutr 1992;16:538-544.
Rushdi RA et al. Control of diarrhoea by fibre-enriched diet in ICU patients on enteral nutrition: a prospective randomized controlled trial. Clin Nutr 2004;23:1344-1352.
Spapen H, et al. Soluble fibre reduces the incidence of diarrhoea in septic patients receiving total enteral nutrition: a prospective, double-blind, randomized, and controlled trial. Clin Nutr 2001; 20(4):301-305.
HomAnn et al. Reduction in diarrhoea incidence by soluble fibre in patients receiving total or supplemental enteral nutrition. J Parenter Enteral Nutr 1994;18:485-490.
HomAnn et al. Reduction in diarrhoea incidence by soluble fibre in patients receiving total or supplemental enteral nutrition. J Parenter Enteral Nutr 1994;18:485-490.