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Advancing the Therapeutic Role of Nutrition
Capture insights into how the therapeutic role of nutrition is advancing today, for tomorrow and together through the
collaboration between healthcare professionals, patients, breakthrough biotech leaders and Nestlé Health Science.
The quest for innovation is strong across fields as diverse as gastrointestinal sensitivities, oncology, infant food
allergy to new technology platforms such as the microbiome and amino acids; it is an innovation frontier expanding
the boundaries of nutrition, health and wellness.
Sharing Solutions for Gastrointestinal Sensitivities
Gastrointestinal sensitivities – including Irritable Bowel Syndrome (IBS) – are a major personal and health economic
burden. Managing IBS can cost up to 20bn dollars in the USA alone.1
Learn how Nestlé Health Science is helping advance the adoption of a pioneering dietary approach – developed by
experts at Monash University, Australia – that limits dietary sugars associated with IBS symptoms.
1 Reference: https://www.ncbi.nlm.nih.gov/pubmed/15298528
Inspired by a Shared Goal: Seizure Control
Pediatric epilepsy impacts not just the child, but also the wider family. A significant proportion of patients don't
respond to mainline drugs but experts are advancing understanding and adoption of ketogenic dietary therapy. It
switches patient’s metabolism to burning fat rather than carbohydrates as a source of energy.
Innovative products such as those developed by Vitaflo, have a key role as part of a wider educational effort to
enable parents and carers to make a palatable diet that patients can adhere to. Seizure control is transforming
Mastering the Microbiome
The ability to analyze microorganisms is today unraveling the mysterious of the microbiome – the 100 trillion
microorganisms that live within us. An unhealthy or so-called dysbiotic microbiome is now understood to be an
underlying cause of a range of health conditions.
Nestlé Health Science partner, Seres Therapeutics, is a leader in the field, exploring its microbial strains to
develop therapeutics that aim to make the microbiome well again. An ability to diagnose, feed and treat the
microbiome – creating a transformational health technology platform is within reach.
Fast Forwarding Therapies: From the Food Proteome
Amino acids have long been recognized as the building blocks of protein, but today breakthroughs are being made
revealing that amino acid imbalance may have be causal factor in a multitude of disease states.
Nestlé Health Science partner Axcella Health is exploring the human diet to identify proteins that have the amino
acid signature capable of restoring cellular balance and thereby treating the underlying cause of the disease. It’s
a new therapeutic modality in the making.
Shortening the Journey: in diagnosing Cow’s Milk Protein Allergy
Cow’s Milk Protein Allergy is the most common infant food allergy in the first year of life; yet it’s range of
non-specific symptoms make it difficult to recognize, leading to delays in therapeutic intervention.
Experts, supported by Nestlé Health Science, are however introducing a simple to use scoring tool – the Cow’s Milk
Related Symptom Score – enabling primary healthcare professionals to interpret symptoms and consider earlier
intervention. An innovative skin patch diagnostic tool is also in development in this dynamic field of therapeutic
First "CDED Expert" training day
CWhat do leading IBD experts say about the Crohn's Disease Exclusion Diet (CDED)? Learn more from the experts behind
the diet and the clinical trials in the video from the first "CDED Expert" training day that took place in
Copenhagen, March 2019.
Role of Mitochondrial Dysfunction in Age Associated Cellular Decline (AACD)
Often with aging, many adults experience exhaustion, fatigue, muscle weakness, and physical impairment. Because
mitochondria are the “power plant” responsible for energy production and metabolism in our cells, organs, and entire
body, mitochondrial dysfunction may be at the basis of these symptoms and the loss of functionality that is common
Join Dr. Matteo Cesari, MD PhD, to understand the role that mitochondrial dysfunction plays in age-related conditions
and how acting on the mechanisms of cellular aging may help how we manage our health.
Age Associated Cellular Decline (AACD) – Mechanisms and Perspectives Relevant to Undernutrition, Sarcopenia and
Frailty in Older Adults
Every day in clinical practice, doctors care for patients with age-related conditions at risk for loss of
functionality. Intervening on the biological mechanisms of aging—including mitochondrial dysfunction—is a promising
solution for the management and prevention of age-related conditions that can address patients’ needs, their quality
of life and functionality.
Join Dr. Matteo Cesari, MD PhD, to understand several hallmarks of aging and how acting on cellular mechanisms, such
as mitochondrial dysfunction, has potential to address the symptoms and needs of aging adults.
The Impact of Age Associated Cellular Decline on Bioenergetics and Functional Impairment
People age differently and there are different patterns of healthy vs. unhealthy aging. Notably, quite a bit of data suggest that lifestyle habits—such as regular exercise and physical activity—promote better mitochondrial function and energy metabolism in older adults. In comparison, inactivity or disuse are detrimental to muscle functionality and Age Associated Cellular Decline due to mitochondrial dysfunction.
Join Dr. Bret Goodpaster, PhD, to understand the importance of mitochondrial function on healthy aging, the impact of mitochondrial dysfunction on unhealthy aging, and how lifestyle habits (physical activity and nutrition) may improve energy metabolism—the efficiency of mitochondrial energy metabolism.
The Importance of Mitochondrial Dysfunction with Aging and Effects of Nutrition and Lifestyle on Energy Metabolism
The body has trillions of mitochondria that tend to dysfunction with older age. As mitochondria serve to convert nutrients into energy to power physical function, it’s important to better prevent age-related declines in mitochondrial function. Cellular nutrition that targets mitochondrial energy metabolism has the potential to impact some of the negative effects of aging.
Join Dr. Bret Goodpaster, PhD, to understand the importance of mitochondrial function on healthy aging, emerging indicators of mitochondrial dysfunction in older adults, and how lifestyle habits (physical activity and nutrition) may improve energy metabolism which is important for how we move and function daily.
Undernutrition, Sarcopenia and Frailty. Is there a Link?
There is clear evidence that Undernutrition, Sarcopenia and Frailty are different but close related conditions associated with adverse health outcomes in older adults. Age-related physiological, psychological, ambient and social factors determine the final relationship between these three conditions. Multicomponent interventions that include diet advise, protein intake, nutritional supplementation, physical exercise and polypharmacy review have demonstrated benefits on the three conditions, and with a synergistic benefit when prescribed together.
Join Prof Pedro Abizanda, MD, PhD, to understand why a multicomponent interventions that include diet advise, protein intake, nutritional supplementation, physical exercise and polypharmacy review have benefits on the three conditions, and with a synergistic benefit when prescribed together.
23 mins; Satellite Symposium, 41st ESPEN Congress on Clinical Nutrition and Metabolism
Oral Nutritional Support in Medical Inpatients - Is it Worth the Effort?
The recently published Effect of early nutritional support on Frailty, Functional Outcomes and Recovery of malnourished medical inpatients Trial (EFFORT) asked the basic question of whether nutritional therapy based on different nutritional components during the hospital stay improves clinical outcomes of medical patients at nutritional risk compared to standard hospital food.
Join Prof Philipp Schuetz, MD, PhD, to understand why an individualized nutritional support to reach protein and energy goals reduces the risk of adverse clinical outcomes in medical inpatients at nutritional risk
19 minutes ; Satellite Symposium, 41st ESPEN Congress on Clinical Nutrition and Metabolism Duration
A short interview with Prof Pedro Abizanda, MD, PhD. Undernutrition, Sarcopenia and Frailty. Is there a Link?
A short interview with Prof Philipp Schuetz, MD, PhD. Oral Nutritional Support in Medical Inpatients - Is it Worth the Effort?