ANGIOEDEMA

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Angioedema is a well-demarcated oedema or swelling of the subcutaneous or interstitial tissue.2 Angioedema is not itchy but may be painful and warm. 1 Angioedema primarily affects the face, lips, mouth upper airway and the extremities.1
What causes angioedema in infants?
The most common causes of angioedema in infants include food allergens, such as cow’s milk protein.3 Exposure to insect bites, some medications, or latex can also result in angioedema.4
Angioedema as a symptom of Cow’s Milk Protein Allergy
Acute Angioedema in infants is one of the many cutaneous symptoms of Cow’s Milk Protein Allergy (CMPA), primarily affecting the lips or eyelids.5 Angioedema occurs in about 10% of infants with CMPA.2

Signs and symptoms related to CMPA
The majority of infants affected with CMPA have at least two symptoms affecting at least two different organ systems.5,6
Having an awareness of the most common symptoms of CMPA can help you to make an earlier diagnosis of CMPA in your patients.
CoMiSS® awareness tool
The Cow’s Milk-related Symptom Score (CoMiSS)® is a simple, fast and easy-to-use awareness tool designed to help you more easily recognise the signs and symptoms that can be cow’s milk-related in infants and young children.

If you suspect your patient is suffering from symptoms that may be suggestive of CMPA, use the CoMiSS® tool to score and assess the likelihood of CMPA.
OTHER SYMPTOMS OF COW'S MILK PROTEIN ALLERGY
References |
1. K Brown., et al. Med J Aust. 2006:185;5:285–9 2. Silva IL., et al. Allergy. 2008:63:1071–76 3. Younker J. and Soar J. Nurs Crit Care. 2010;15(2):94–8 4. Lifschitz C. and Szajewska H. Eur J Pediatr. 2015;174:141–50 5. Høst A. Pediatr Allergy Immunol. 1994;5:1–36 |